The allergic reaction known as anaphylaxis occurs in 0.5% to 5% of the U.S. population as a result of insect stings. At least 40 deaths per year result from insect sting anaphylaxis. The majority of the insect stings in the United States come from wasps, yellow jackets, hornets and bees. The red or black imported fire ant now infects more than 260 million acres in the southern United States, where it has become a significant health hazard and may be the number one agent of insect stings. What is a normal reaction to an insect sting and how is it treated? The severity of an insect sting reaction varies from person to person. A normal reaction will result in pain, swelling and redness confined to the sting site. Simply disinfect the area (washing with soap and water will do) and apply ice to reduce swelling. A large local reaction will result in swelling that extends beyond the sting site. For example, a sting on the forearm could result in the entire arm swelling twice its normal size. Although alarming in appearance, this condition is often treated the same as a normal reaction. However, because this condition may persist 2 to 3 days, antihistamines and corticosteroids are sometimes prescribed to lessen the discomfort. Fire ants, yellow jackets, hornets and wasps can sting repeatedly. Honeybees have barbed stingers, which are left behind in their victim’s skin. These stingers are best removed by a scraping action, rather than a pulling motion, which may actually squeeze more venom into the skin. Almost all people stung by fire ants develop an itchy, localized hive or lump at the sting site, which usually subsides within 30 to 60 minutes. This is followed by a small blister within 4 hours. This usually appears to become filled with pus by 8 to 24 hours. However, the material seen is really dead tissue and the blister has little chance of being infected unless it is opened. When healed, these lesions may leave scars. Treatment for fire ant stings is aimed at preventing secondary bacterial infection, which may occur...